The Physician’s Global Assessment (PGA) is a clinical tool used to measure psoriasis severity based on a clinician’s overall impression of lesion appearance. It typically uses a 5- or 6-point scale ranging from “clear” to “severe,” evaluating factors such as erythema (redness), plaque thickness, and scaling. Regulatory agencies, including the FDA, often accept PGA scores of “clear” (0) or “almost clear” (1) as primary efficacy endpoints in psoriasis clinical trials.