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TFS TFS HealthScience | Contract Research Organization | Global Resourcing Provider | CRO
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Internal Medicine

Therapeutic expertise Internal Medicine

Internal medicine clinical trials from first-in-human to real-world evidence.

We pair senior medical oversight with established global site networks to run chronic, acute and rare internal medicine studies. Expertise spanning respiratory, endocrinology, cardiovascular, metabolic and beyond.
Talk to our internal medicine team

350+

Completed trials

8,000+

Investigator sites across 25+ countries

150,000+

Patients enrolled

Therapeutic depth across the internal medicine spectrum

Internal medicine trials often involve complex protocols, long study durations and patients living with chronic conditions and comorbidities. Our teams have supported 50+ indications, from high-prevalence chronic diseases to rare and complex conditions.

Respiratory
COPD · Asthma · Emphysema · Bronchiectasis ·
Pulmonary fibrosis · Pulmonary arterial hypertension · Acute respiratory distress syndrome · Cystic fibrosis · Respiratory insufficiency

Endocrinology and metabolic
Diabetes, including type 1 · Diabetes-related disorders · Hypercholesterolaemia and hyperlipidaemia · Thyroid disorders

Cardiovascular 
Thrombosis · Vascular disorders 

Gastrointestinal
Irritable bowel syndrome · Colitis and ulcerative colitis · Crohn’s disease · Nutritional disorders · Ileostomy and ostomy · Constipation · Diarrhoea · Diverticulitis · Liver cirrhosis · Mucositis · Pancreatitis · Gastritis

Solomon Kamal-Uddin

Medical Advisor

“Internal medicine trials rarely enrol patients with a single condition. Comorbidities that may impact over long follow-up periods shape key protocol decisions. When medical oversight starts at design, eligibility criteria can reflect real patients leading to more inclusive recruitment and outcomes that reflect real world populations.”

Our internal medicine unit runs on a vertical model, with every team member assigned for their internal medicine expertise and dedicated solely to the unit.

Know your team

How we secure your clinical pathway

Clinical continuum

Built-in flexibility, from a single CRA to full global trials.

Strategic resourcing, FSP and full-service clinical development, working as one team. Scale capacity across 40 countries, eliminating vendor handoffs while preserving protocol knowledge in the room the whole way through.

Therapeutic depth

Fast decisions through specialized clinical depth.

We restrict our focus to five complex therapeutic areas. Our specialized leads theyhold direct decision-making authority, fast-tracking approvals and solving site bottlenecks with scientific authority.

Teams that stay

True peers, driven by scientific urgency.

TFS holds an 88% retention rate, 8 points above the industry average. That means the senior scientific peer who joins your study is still there at database lock.

Trial security

Risk flagged early. Execution made visible.

Rooted in our Swedish heritage, we bring disciplined methodology and transparent communication to every study. We deliver real-time data integrity, flag protocol issues before they cost you time, and maintain regulatory compliance at every milestone.

Medical and operational
internal medicine leadership

Åsa Carlsheimer

Vice President, Head of Internal Medicine and Neuroscience

Lakshmi Guduri

Senior Director, Project Management, Internal Medicine & Neuroscience

Solomon Kamal-Uddin

Medical Advisor

Karoly Kamarell

Senior Director Operational Strategy and Delivery

One team, whether you need a single specialist or a full trial.

Clinical development

Access specialized clinical experts who integrate directly into your internal teams, matching your operational demands as they shift.
— Rapid deployment of validated
clinical professionals.

— Flexible capacity management 
tailored to pipeline shifts.
Phase I to III Phase IV & RWE

Strategic solutions

We embed life sciences expertise wherever your programme needs it: a single expert consultant, a dedicated FSP team, a hybrid model or a fully managed function. Every option draws on 60,000+ active professional profiles and runs on one continuum, with built-in flexibility, trial security and senior teams that stay from day zero.
— Expert consultants matched to your study, on average within five days.

— Dedicated FSP teams, line-managed by TFS and working to your SOPs.

— Hybrid models that combine FSP and full service under one governance.

— Managed functions we run for you, from oversight to systems.
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End-to-end delivery

Full-service trial execution, backed by therapeutic depth and teams that stay.
— Full-lifecycle protocol management 
from design to database lock.

— Scientific leadership across 5 specialized 
therapeutic areas.

— Stable project teams ensuring continuous 
data quality and safety.
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Quality Management

Three services. One independent quality function, standalone or embedded across your clinical portfolio.
— Audit & programme management: risk-based GxP audits to detect risks early and drive continuous improvement.

— Inspection readiness: targeted assessments, mock inspections and SME preparation for regulatory scrutiny.

— Quality oversight: ICH E6(R3)- and ICH E8(R1)-aligned oversight across studies and vendors.
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Securing the path for sponsors’ science.

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Updates to keep your trials
moving forward.

News VERIGRAFT and TFS HealthScience partner on pivotal Phase II/III trial of personalized tissue-engineered vein for chronic venous insufficiency
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Clinical operations & outsourcing FAQs.

What clinical outsourcing models does TFS provide?
We deliver three modular frameworks under a single contract: Strategic Resourcing, Functional Service Provider (FSP), and Full-Service Trials. This model elasticity allows you to scale clinical capacity fluidly as your pipeline demands, eliminating vendor handoffs.

What is the geographic footprint and reach of TFS?
Founded in Lund, Sweden, we operate as a global CRO with active regulatory and clinical reach across 40 countries. We combine comprehensive multi-region execution with specialized infrastructure and investigator networks across Europe and the Nordics.

How does TFS maintain clinical study continuity?
We maintain an industry-leading CRA turnover rate of 14%, significantly outperforming the 20% sector average. This team stability ensures consistent protocol knowledge, reduces management burden, and protects your data integrity.

Which therapeutic areas does TFS specialize in?
We concentrate our medical, clinical, and regulatory capabilities exclusively within five core areas: Dermatology, Internal Medicine, Neuroscience, Oncology, and Ophthalmology, backed by a track record of 1,800+ completed trials.