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Internal Medicine

Solution-driven partnerships
Passion, quality and trustful collaboration

TFS HealthScience combines our internal medicine expertise and operational excellence with local knowledge and the highest quality delivery to help you find the best path to deliver your project on time and on budget.

Trusted science, quality, and passion

Many customers originally came to TFS based on our reputation for dermatologically-experienced resources and delivery of high-quality clinical development services. They stay with us because we listen, and we deliver solutions on-time and on-budget.

Regulatory strategy

Deep knowledge of global regulatory landscape as well as country-specific differences and advantages across Europe and North America

Operational excellence

Track record of delivering hundreds of studies using our accelerated submission and recruitment processes

Clear communication

Trust with our customers built through solid processes, project management, and transparent communications

Skill and precision

Therapeutically-trained operations team, including project managers, physicians, start-up teams, CRAs, data managers, and medical monitors in pivotal trials with extensive global and local knowledge

Expert guidance

Medical and strategic experts who provide advice and support throughout the clinical development journey

TFS Internal Medicine at a glance

>350 clinical studies in the last 5 years
>3,000 investigator sites in the last 5 years
>50 ongoing studies

TFS has supported nearly 500 clinical trials in in internal medicine and related areas across all phases

TFS Internal Medicine Experience by Indication

TFS’ primary Internal Medicine unit indication experience includes:


  • Acute Coronary Syndrome
  • Cardiac Arrest
  • Atherosclerosis
  • Cholesterol
  • Heart Failure (Acute and Congestive)
  • Hypotension
  • Low Ferritin
  • Occlusive Arterial Disease (OAD)
  • Pulmonary Vascular Disease (PVD)
  • Peripheral Arterial Disease (PAD)/ Peripheral Vascular Disease (PVD)
  • Recurrent Deep Vein Thrombosis
  • Vascular Calcification
  • Aneurysm
  • Atrial Fibrillation
  • Cardiovascular Surgery
  • Giant Cell Arteritis
  • Hypertension
  • Intermittent Claudication
  • Myocardial Infarction
  • Oxidative Damage
  • Pulmonary Arterial Hypertension
  • Raynaud’s Disease
  • Stent Implantation
  • Venous Thromboembolism


  • Carnitine Deficiency
  • Diabetic Macular Edema
  • Dyslipidaemia
  • Growth Hormone Deficiency
  • Hypercholesterolemia
  • Hypernatremia
  • Hypoglycemia
  • Weight Loss
  • Secondary Hyperparathyroidism
  • Type 2 Diabetes Mellitus
  • Vitamin Deficiency Disorders
  • Diabetes
  • Diabetic Nephropathy
  • Growth Disorders
  • Hepatology
  • Hyperlipidemia
  • Hyperparathyroidism
  • Hypoparathyroidism
  • Osteoporosis
  • Type 1 Diabetes
  • Urea Cycle Disorders
  • Nutrition/Nutritional Disorders


  • Barrett’s Oesophagus
  • Colitis
  • Crohn’s Disease
  • Diverticulitis
  • Esophageal Strictures
  • Ileostomy
  • Inflammatory Bowel Disease (IBD)
  • Liver Cirrhosis
  • Lymphocytic Colitis
  • Biliary Strictures
  • Constipation
  • Diarrhea
  • Enteral feeding
  • Gastritis
  • Incisional Infections in Colorectal Surgery Patients
  • Nutrition
  • Pancreatic Diseases
  • Parenteral Nutrition
  • Short Bowel Syndrome
  • Irritable Bowel Syndrome (IBS)
  • Liver Lesions
  • Mucositis
  • Ostomy
  • Pancreatitis
  • Pinworm & Whipworm
  • Ulcerative Colitis


  • Acute Respiratory Distress Syndrome
  • Bronchial Thermoplasty
  • Chronic Bronchitis
  • Chronic Obstructive Pulmonary Disease (COPD)
  • Diffuse Parenchymal Lung Disease
  • Excess Post-Exercise Oxygen Consumption (EPOC)
  • Idiopathic Pulmonary Fibrosis
  • Pulmonary Fibrosis
  • Respiratory Infectious diseases
  • Transfusion Hemosiderosis
  • Asthma
  • Bronchiectasis
  • Chronic Cough
  • Cystic Fibrosis
  • Emphysema
  • Histamine receptors
  • Pulmonary Alveolar Proteinosis (PAP)
  • Pulmonary Inflammation
  • Respiratory Insufficiency

Case Study: Team collaboration pulled this type 1 diabetes study to the finish line, overcoming challenges and exceeding expectations

The complexities of clinical trials require a coordinated effort in the best of times. With a delay in the first-patient-in, six protocol amendments, and a 33% increase in patients, this study was at risk of falling behind schedule. COVID-19 restrictions threatened to further complicate study timelines. TFS and the client partnered to address each challenge presented and bring the study to a successful on-time conclusion.

Population: 12-25 year olds diagnosed with T1D within the six months prior to screening
Indication: Type 1 Diabetes
Number of Patients: 109
Sites: 18
Regions: Sweden, Spain, Czech Republic and the Netherlands

Read about the challenges and TFS solution
type 1 diabetes case study

One project, one team

The TFS Internal Medicine team understands the intricacies of clinical development and can partner with you to develop a strategy that helps ensure your product’s success. In our experience, working together maximizes the chances of success, and when we work with you, our knowledge and resources can be applied to your trial.

TFS CNS Expert

Anne-Marie Nagy, PhD


  • Specialized internal medicine indications in women’s health and pulmonary inflammatory diseases
  • Operational oversight of large clinical programs in neurology, psychiatry, pain, and cystic fibrosis across all phases in NA, EMEA, South Africa, ASIAPAC, and LA, as well as peri-post approval drug market

We listen to deliver

From big-picture strategy to implementation of the smallest detail, we demonstrate our expertise at every stage of the clinical development process. We are just as thorough when working with our clients—talk to us about your project.

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