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TFS TFS HealthScience | Contract Research Organization | Global Resourcing Provider | CRO
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Neuroscience

Therapeutic expertise Neuroscience

Neuroscience clinical trials expertise across 30+ CNS indications

From multiple sclerosis, Alzheimer’s and Parkinson’s disease to psychiatry, pain and rare neurological disorders, one dedicated neuroscience unit runs your trial with every key function in-house.
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140+

Completed trials

3,000+

Investigator sites across 30+ countries

39,000+

Patients enrolled

Built for the realities of CNS research

Subjective rating scales, high placebo response and slowly progressing disease can hide a real effect. Our neuroscience team plans against each one. We build in rater training, keep the same certified rater with each patient and standardise every assessment and we confirm eligibility before randomisation, reducing the variability and ensuring high quality endpoint results.

Cell and gene therapies in rare neurological conditions

Our team has hands-on experience running complex cell and gene therapy trials in rare neurological conditions. We understand the specific challenges these programs face and build risk mitigation into the study from the start.

Neurology
Alzheimer’s Disease · Amyotrophic Lateral Sclerosis · Cognitive Impairment · Epilepsy · Multiple Sclerosis · Parkinson’s Disease · Stroke · Traumatic Brain Injury

Psychiatry and sleep
Addiction · Anxiety · Bipolar Disorder · Chronic Fatigue Syndrome · Circadian Rhythm Sleep Disorders · Conduct Disorders · Depression · Schizophrenia · Major Depressive Disorder · Post-Traumatic Stress Disorder (PTSD) · Substance Use Disorders.

Rare neurological disorders
Duchenne Muscular Dystrophy · Huntington’s Disease · Rett Syndrome · Batten Disease · Prion Diseases

Lakshmi Guduri

Senior Director Project Management

“Maximizing study integrity is critical in any clinical trial, but even more so in Neurodegenerative trials, where inappropriate participant enrollment frequently leads to trial failure. TFS addresses this challenge by implementing consistent rater training, early subject eligibility reviews, diagnostic adjudication, and transparent placebo counselling at the consent stage, we transform the complexities of slowly progressing diseases into clean, actionable data.”

Clinical operations, medical and safety, data, regulatory and quality all sit inside our neuroscience unit. One team shares every decision, so everything is secured by experience and nothing waits on a hand-off.

Know your team

How we secure your clinical pathway

Clinical continuum

Built-in flexibility, from a single CRA to full global trials.

Strategic resourcing, FSP and full-service clinical development, working as one team. Scale capacity across 40 countries, eliminating vendor handoffs while preserving protocol knowledge in the room the whole way through.

Therapeutic depth

Fast decisions through specialized clinical depth.

We restrict our focus to five complex therapeutic areas. Our specialized leads theyhold direct decision-making authority, fast-tracking approvals and solving site bottlenecks with scientific authority.

Teams that stay

True peers, driven by scientific urgency.

TFS holds an 88% retention rate, 8 points above the industry average. That means the senior scientific peer who joins your study is still there at database lock.

Trial security

Risk flagged early. Execution made visible.

Rooted in our Swedish heritage, we bring disciplined methodology and transparent communication to every study. We deliver real-time data integrity, flag protocol issues before they cost you time, and maintain regulatory compliance at every milestone.

Medical and operational
neuroscience leadership

Åsa Carlsheimer

Vice President, Head of Internal Medicine and Neuroscience

Lakshmi Guduri

Senior Director, Project Management, Internal Medicine & Neuroscience

Solomon Kamal-Uddin

Medical Advisor

Karoly Kamarell

Senior Director Operational Strategy and Delivery

One team, whether you need a single specialist or a full trial.

Clinical development

Access specialized clinical experts who integrate directly into your internal teams, matching your operational demands as they shift.
— Rapid deployment of validated
clinical professionals.

— Flexible capacity management 
tailored to pipeline shifts.
Phase I to III Phase IV & RWE

Strategic solutions

We embed life sciences expertise wherever your programme needs it: a single expert consultant, a dedicated FSP team, a hybrid model or a fully managed function. Every option draws on 60,000+ active professional profiles and runs on one continuum, with built-in flexibility, trial security and senior teams that stay from day zero.
— Expert consultants matched to your study, on average within five days.

— Dedicated FSP teams, line-managed by TFS and working to your SOPs.

— Hybrid models that combine FSP and full service under one governance.

— Managed functions we run for you, from oversight to systems.
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End-to-end delivery

Full-service trial execution, backed by therapeutic depth and teams that stay.
— Full-lifecycle protocol management 
from design to database lock.

— Scientific leadership across 5 specialized 
therapeutic areas.

— Stable project teams ensuring continuous 
data quality and safety.
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Quality Management

Three services. One independent quality function, standalone or embedded across your clinical portfolio.
— Audit & programme management: risk-based GxP audits to detect risks early and drive continuous improvement.

— Inspection readiness: targeted assessments, mock inspections and SME preparation for regulatory scrutiny.

— Quality oversight: ICH E6(R3)- and ICH E8(R1)-aligned oversight across studies and vendors.
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Securing the path for sponsors’ science.

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The resourcing decision : Full-service, FSP or specialist. Which one actually fits your programme?

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Juneteenth and the next chapter of medicine

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This Pride Month see the life behind every number

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Updates to keep your trials
moving forward.

News VERIGRAFT and TFS HealthScience partner on pivotal Phase II/III trial of personalized tissue-engineered vein for chronic venous insufficiency
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News Our 2025 sustainability year in review: the highlights
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News Europe's clinical development landscape: does the EU hold a busted flush or a full house?
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News Expanding the Frontiers of Neuroscience: TFS Strengthens Its Gene Therapy Portfolio in Neurodegenerative Diseases
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Clinical operations & outsourcing FAQs.

What clinical outsourcing models does TFS provide?
We deliver three modular frameworks under a single contract: Strategic Resourcing, Functional Service Provider (FSP), and Full-Service Trials. This model elasticity allows you to scale clinical capacity fluidly as your pipeline demands, eliminating vendor handoffs.

What is the geographic footprint and reach of TFS?
Founded in Lund, Sweden, we operate as a global CRO with active regulatory and clinical reach across 40 countries. We combine comprehensive multi-region execution with specialized infrastructure and investigator networks across Europe and the Nordics.

How does TFS maintain clinical study continuity?
We maintain an industry-leading CRA turnover rate of 14%, significantly outperforming the 20% sector average. This team stability ensures consistent protocol knowledge, reduces management burden, and protects your data integrity.

Which therapeutic areas does TFS specialize in?
We concentrate our medical, clinical, and regulatory capabilities exclusively within five core areas: Dermatology, Internal Medicine, Neuroscience, Oncology, and Ophthalmology, backed by a track record of 1,800+ completed trials.